Autoimmune diseases

Autoimmune diseases affect fertility- fact or myth?

Autoimmune diseases can cause difficulty conceiving. Lupus, rheumatoid arthritis, Type A diabetes etc. are some of the autoimmune diseases that can increase the risk of infertility among women. But part for these diseases, there are some specific autoimmune diseases that are needed in case you have infertility problem or having problem conceiving.

What is an autoimmune disease?

An autoimmune disease is a particular type of condition where your own immunity system mistakenly attacks your body. Our immunity system is responsible to detect presence of foreign cells in the body and then fights it. These foreign cells can be various types of bacteria, viruses etc. Under autoimmune condition the immunity system fails to distinguish between host cells and foreign cells. Then it releases autoantibodies, a type of protein that attacks the healthy cells. There are some autoimmune diseases that attack only a particular organ. For example, Type 1 diabetes damages the pancreas system. Autoimmune diseases can attack the thyroid glands in your body, joint, ovaries etc. Particularly, if it attacks the ovaries then it can reduce ovarian reserve, or in simple word, lower the number of eggs in the ovaries. A completely diminished ovarian reserve means infertility.

Tests of Autoimmune diseases regarding Infertility

Women, who are suffering with infertility issues or miscarriage, should go for some specific autoimmune disease tests.

Decreased Ovarian Reserve: This is one of the most recommended tests in case you are facing infertility issues. The test, evaluate levels of Follicle Stimulating Hormone (FSH) and Antimullerian Hormone (AMH). These hormones determine the capacity of ovarian reserve. If the levels are abnormal in respect with your age then maybe you have an autoimmune problem which can be the cause of lowering numbers of eggs in the ovarian. Depending on the result of these tests, then you may need to undergo some other tests as well.

Thyroid Disease: We know that thyroid is a notorious factor against fertility among women. Even a mild thyroid can reduce the change of pregnancy among women and can lead to miscarriage. So to speak, autoimmune thyroid disease is very common among women.

Antiphospholipid Antibody Syndrome: Placental abruption because of a clot or some other reason can be the reason of miscarriage and pregnancy complication. Antiphospholipid Antibody Syndrome is a type of autoimmune disease that produces antibodies against the placental tissue. As a result, this increases the chance of blood clot in the placenta and increases the risk of pregnancy complications.

Anti-sperm Antibodies: Immunity system in men also can create antibodies that can affect the fertility. Men sometimes create antibodies to their own sperm that that decrease the motility or fertilizing ability of the sperm. Though there is no specific cause of it, but it can be due to various reasons, such as testicular trauma or because of a surgery like vasectomy, varicocele repair or vasectomy reversal.


Treatments of autoimmune diseases need both proper diagnosis and treatments of the problems. Your doctor will recommend a combination tests and medications according to the condition of the disease. The antinuclear antibody test (ANA) is the primary test for determining any presence of autoimmune diseases in the body. A positive ANA blood test may suggest presence of autoimmune diseases in the body. Then you may be advised to take certain nonsterodial anti-inflammatory drugs (NSAIDs) and immune-supressing drugs.

It is quite evident through this brief discussion that autoimmune diseases can severely impact your fertility and overall health condition as well. Therefore, once you are diagnosed with autoimmune disease, specific treatments should be started as soon as possible. Autoimmune diseases are not completely curable but bringing them under control can help you to eradicate the complications of fertility. Some other fertility treatments may also be required with it.

For more queries you can always consult with the best fertility expert in Siliguri

About Dr. Prasenjit Roy

Dr. Prasenjit Roy attained medical qualification from premier institutions in India. He also received Fellowship in Reproductive endocrinology and Infertility under Dr. Amit from Tel-Aviv University, Israel. Dr. Prasenjit attained medical qualification from premier institutions in India and achieved his ultimate goal of being an elite name in the Infertility business. His passion for helping hopeful couples to lit their unfulfilled lives has helped him achieve this honorable position in this field. He is fully involve with infertility counseling of patient, Doing Intrauterine Insemination, In-Vitro Fertilization, Egg Donation, Surrogacy, TESA, TESE. He also received his Fellowship in Reproductive endocrinology and Infertility from the Tel-Aviv University, Israel.

Check Also

Advancements in PRP Therapy: A Leap Forward in Regenerative CareThe Science Behind PRP and Its Therapeutic Applications

Platelet-Rich Plasma (PRP) therapy marks a significant milestone in the journey towards advanced regenerative medical …

Leave a Reply

Your email address will not be published. Required fields are marked *