Gastroenterology Clinical Trials

What Procedures Do Gastroenterology Clinical Trials Follow?

Gastroenterology clinical trials perform a number of non-surgical procedures. This may include:

  • Upper endoscopy, which helps diagnose conditions of the food pipe, stomach, and small intestine
  • Endoscopic ultrasounds that examine the upper and lower GI tract and other internal organs
  • Colonoscopy, which can detect colon cancer or colon polyps
  • Endoscopic retrograde cholangiopancreatography, which identifies stones or tumors in the area of ​​the bile ducts
  • Sigmoidoscopy, which evaluates for blood loss or pain in the lower colon
  • Liver biopsy, which evaluates inflammation and fibrosis in the liver
  • Capsule endoscopy and double-balloon enteroscopy, both of which examine the small intestine
  • Feeding tube insertion to insert feeding tubes into the abdomen

When should you see a gastroenterologist?

Your primary care physician may refer you to a gastroenterology clinical trials if:

  • You have unexplained blood in your stool
  • Have unexplained difficulty swallowing
  • They experience abdominal pain
  • You suffer from digestive problems such as constant constipation or diarrhoea
  • You suffer from constant acid reflux or heartburn

If you are over 50, you may also want to see a gastroenterologist for preventive care, as you may be at increased risk for colon cancer.

If you are in this age group, you should get regular checkups. If you have a relative with colon cancer, you should ask your doctor when to start screening.

Who Are Gastroenterology Clinical Trials?

Gastroenterologists specialize in gastrointestinal problems such as IBS, ulcers, polyps, and chronic heartburn. These doctors have 3 years of medical school and 5 to 6 years of additional training. They usually don’t perform surgery, but they do perform endoscopic procedures that can help them diagnose and treat many gastroenterology clinical trials conditions.

Your primary care physician will most likely recommend that you see a gastroenterologist if they notice something is wrong with your digestion, if you have stomach pain, or if certain blood tests come back with elevated levels.

A gastroenterologist is a specialized doctor who deals with the diagnosis and treatment of gastroenterology clinical trials diseases in men and women. He also performs endoscopic procedures using instruments that facilitate a better visualization of the GI tract and make an accurate diagnosis. However, operations are performed by those known as surgical gastroenterologists. The gastrointestinal system is responsible for the movement and digestion of food in the intestine, the assimilation of nutrients and the removal of waste products.

The gastrointestinal tract consists of the following organs:

  1. Mouth (salivary glands, tongue)
  2. Pharynx
  3. Esophagus
  4. Stomach
  5. Small intestine
  6. Colon
  7. Liver
  8. Gallbladder
  9. Pancreas
  10. Rectum
  11. Anus

However, any disease related to the mouth is treated by a dentist or oral surgeon, while any disease related to the anus or anus is treated by a proctologist.

What conditions do gastroenterology clinical trials treat?Clinical Trials

Some of the most common disorders treated by a gastroenterologist are listed below:

Acid Reflux

This is the most common condition that manifests itself as a burning sensation in the upper part of the stomach. The burning sensation is also known as heartburn. This occurs due to the regurgitation of stomach acid into the food pipe. It can be treated with dietary changes.

GERD, or gastroesophageal reflux disease – This occurs when acid reflux becomes more frequent and symptoms worsen. This affects the lower esophageal sphincter, the ring that sits between the esophagus and the stomach.

Hepatitis C

This is a liver disease caused by the hepatitis C virus. This virus can cause both acute and chronic hepatitis. Symptoms can vary from mild to severe and can last from a few weeks to a lifelong illness.


Yellow discoloration of the skin, mucous membranes, and whites of the eyes due to increased levels of bilirubin in the blood. Jaundice is a symptom of some underlying chronic disorder. Bilirubin is a byproduct of the natural breakdown and destruction of red blood cells in the body.


Commonly known as piles, refer to swollen veins in the anus and lower part of the anus, similar to varicose veins. These hemorrhoids can develop inside the anus or under the skin around the anus. Those found inside the anus are called internal hemorrhoids, and those under the skin are called external hemorrhoids.


This is a disease in which the pancreas is inflamed. This occurs when digestive enzymes are activated before being released into the small intestine and attacking the pancreas. Pancreatitis can be acute or chronic. Acute pancreatitis is a sudden inflammation occurring over a short period of time, while chronic pancreatitis is a long-term inflammation of the pancreas.

The most common procedures performed by top gastroenterologists in India are:

  • Colonoscopy – a procedure to detect colon polyps or colon cancer
  • Endoscopic ultrasound – a procedure used to examine the upper and lower gastroenterology clinical trials tract and other internal organs.
  • Liver biopsy – this is done to access inflammation and fibrosis
  • Sigmoidoscopy – to evaluate blood loss or pain during stool.
  • Capsule endoscopy – to examine the small intestine
  • Endoscopic retrograde cholangiopancreatography – to look for gallstones, tumors or any scarring in the bile duct.
  • Double balloon enteroscopy – this is also done to examine the small intestine.

7 Signs It’s Time to See a Gastroenterology Clinical Trials

If you have unexplained or frequent digestive problems, such as abdominal discomfort or changes in bowel movements, someone has probably told you to see a gastroenterologist, sometimes referred to as a GI doctor.

But if you’ve never seen a gastroenterologist before, you may not be sure if your digestive symptoms really warrant a visit to a specialist. You may even be asking:

What is a gastroenterologist?

Dr. Kerri Glassner, a gastroenterologist at Houston Methodist, explains everything you need to know if you’re deciding whether it’s time for a visit, including what to expect at your first appointment.

What does a gastroenterologist do?

A gastroenterologist is a specialist with expertise in disorders and diseases that affect the digestive system – which includes the gastrointestinal tract (esophagus, stomach, small intestine, colon, rectum, and anus) as well as the pancreas, liver, bile ducts, and gallbladder. .

Digestive disorders and problems that a gastroenterologist treats include:

  • Unexplained changes in bowel movements, including diarrhoea, constipation and blood in the stool
  • Gastroesophageal Reflux Disease (GERD)
  • Heartburn
  • Hemorrhoid
  • Inflammatory bowel disease (IBD), which includes Crohn’s disease and ulcerative colitis
  • Irritable Bowel Syndrome (IBS)
  • Pancreatitis
  • Ulcers

“Gastroenterologists are trained to perform a number of procedures used to diagnose and treat these conditions, such as upper endoscopy, colonoscopy, biopsy, and various endoscopic techniques needed to visualize the digestive system, including endoscopic ultrasound,” explains Dr. Glassner.

When should you see a gastroenterologist?

Here are seven reasons to consider seeing a gastroenterologist:

1. Persistent diarrhea

From food to infection to certain medications, many things can cause a bout of diarrhea. However, if your stool is regularly more liquid than solid, it’s time to see a Vial doctor.

“Chronic diarrhea can be a sign of several different digestive disorders, including IBS, IBD, or small bacterial overgrowth (SIBO),” says Dr. Glassner. “IBS is the most common cause of chronic diarrhea. Fortunately, there are many treatment options your doctor can use to help manage your symptoms.”

2. ConstipationGastroenterologist

Stool frequency ultimately varies from person to person, but Dr. Less than three per week is usually considered constipated, Glassner says. You may also be constipated if your bowel movements are very small, very hard or difficult to pass.

If you are constipated for more weeks than not, consult a gastroenterologist.

“Constipation can have many causes and can be difficult to manage on your own at home,” says Dr. Glassner. “A GI specialist can help determine the likely cause of your constipation and recommend lifestyle changes and medications that can help with more regular bowel movements.”

3. Frequent or severe heartburn

Occasional heartburn shouldn’t worry you, and the good news is that occasional heartburn can usually be managed at home.

But if you have heartburn symptoms more than a few times a week, it could be a sign of GERD, a condition that can damage and scar the lining of the esophagus over time.

“Chronic acid reflux doesn’t go away on its own, so it’s important to get it evaluated by a professional,” says Dr. Glassner. “Untreated, GERD can cause permanent damage to the esophagus. This damage can lead to swallowing problems, cause painful ulcers, and even increase the risk of esophageal cancer.”

4. Feeling unusually bloated

Bloating, which can feel like your abdomen is full or tense, is often caused by problems that lead to excessive gas production, gas sensitivity, or gas that is trapped in the colon.

“Constipation can cause bloating because the longer waste remains in your colon, the more likely it is to be fermented by the resident gas-producing bacteria,” explains Dr. Glassner. “But bloating can also be a sign of IBS, food sensitivities such as lactose intolerance, SIBO (small intestinal bacterial overgrowth) or gastroparesis (partial paralysis of the stomach).

A gastroenterology clinical trials can help you determine exactly what is causing your bloating and the most effective way to treat it.

5. Sudden or severe abdominal pain

We’ve all dealt with abdominal pain, but severe abdominal pain that lasts for hours or abdominal pain that comes on suddenly and intensely is not normal.

“A stomach ulcer or peptic ulcer, which is pain in the lining of the stomach or the first part of the small intestine, can lead to burning pain in the abdomen, especially after eating,” says Dr. Glassner. “An untreated ulcer can cause swelling and scarring that blocks your digestive tract.”

Persistent severe abdominal pain can also be a symptom of gallstones, pancreatitis or liver disease. A gastroenterology clinical trials can help determine the cause of your pain.

6. Rectal bleeding or blood in the stool

If you see blood on the toilet paper or when you flush the toilet, it could be hemorrhoids, a fairly common problem that can usually be managed with home remedies or over-the-counter products.

“However, if hemorrhoids do not respond to this treatment or you get them frequently, a gastroenterologist may recommend more advanced treatments that may help you get relief,” adds Dr. Glassner.

Additionally, don’t assume that blood in the toilet can only mean hemorrhoids.

“Any time you see blood in your stool or have rectal bleeding that is accompanied by changes in your bowel habits or the color or consistency of your stool, it’s important to see a gastroenterologist,” warns Dr. Glassner. “Rectal bleeding isn’t always a big problem, but it can be a sign of a serious medical condition, such as colorectal cancer.”

7. Colonoscopy awaits you

If you’re over 45 or have a strong family history of colorectal cancer, you’ve probably heard your doctor recommend a colonoscopy.

“Most people start having screening colonoscopies at age 45,” says Dr. Glassner. “From there, the frequency varies depending on your results-but if the findings are normal and you have no other risk factors, you just need to repeat the colonoscopy every 10 years.”

And while a colonoscopy may sound uncomfortable, it can save your life. Early detection of colorectal cancer is important – catching it early can lead to less aggressive treatment and a better chance of survival.

What happens during a gastroenterology visit?

If you’ve noticed any of these seven symptoms, it’s time to consider scheduling an appointment with a GI doctor.

At your first appointment, your gastroenterologist:

  • Ask about your digestive symptoms and medical history
  • Recommend any lifestyle changes or medications that may help relieve your symptoms
  • Discuss any tests, screenings or procedures that may be needed

It may be helpful to make a list of your symptoms before your appointment so you don’t forget to ask about any of the problems you are having.

Also read:- Preclinical Oncology CRO Market Risk And Opportunity Assessment And Forecast To 2030

“Through this initial evaluation, your doctor will begin the process of uncovering the gastroenterology clinical trials cause of your digestive problems and begin to address your symptoms,” explains Dr. Glassner. “If your condition is chronic, he’ll also discuss how best to manage your condition over time. Your doctor may also talk to you about additional tests that may be needed if your symptoms don’t improve.”

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